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HiFiBiO to present platform at next-generation antibodies conference

In Uncategorized by nagrazodar

Paris, France, 12 June 2015—HiFiBiO will present its novel, integrated platform for the discovery of differentiated therapeutic antibodies at the Next Generation Antibodies and Protein Analysis Conference: Tools and Technologies, on 15 June 2015, in Ghent, Belgium.

In a presentation, “Deep Mining of Immune Repertoires”, HiFiBiO’s Chief Scientific Officer, Allan Jensen, PhD, will describe the company’s state-of-the-art technologies and integrated workflow for rapidly generating functionally active antibodies against complex targets. The platform uses droplet microfluidics, to achieve high throughput, single cell, function-based screening of entire antibody-secreting B cell populations. Single-cell-specific barcoding and next-generation sequencing, are used to generate paired V-gene sequences from the sorted B-cells. The resulting target specific V-gene repertoires can then be efficiently and rapidly converted to antibodies to accelerate the process of drug candidate selection.